| ADR Ontology |
| ADR Term |
Nephrotic syndrome |
| ADR ID |
BADD_A03027 |
| ADR Hierarchy |
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| Description |
A disorder characterized by symptoms that include severe edema, proteinuria, and hypoalbuminemia; it is indicative of renal dysfunction. [CTCAE] Pathological processes of the KIDNEY without inflammatory or neoplastic components. Nephrosis may be a primary disorder or secondary complication of other diseases. It is characterized by the NEPHROTIC SYNDROME indicating the presence of PROTEINURIA and HYPOALBUMINEMIA with accompanying EDEMA. [MeSH] |
| MedDRA Code |
10029164 |
| MeSH ID |
D009401; D009404; D009404
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ADR Severity Grade (FAERS)
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ADR Severity Grade (CTCAE)
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| Synonym |
| Nephrosis | Nephrosis osmotic | Nephrotic syndrome | Nephrotic syndrome in diseases classified elsewhere | Nephrotic syndrome with lesion of membranoproliferative glomerulonephritis | Nephrotic syndrome with lesion of membranous glomerulonephritis | Nephrotic syndrome with lesion of minimal change glomerulonephritis | Nephrotic syndrome with lesion of proliferative glomerulonephritis | Nephrotic syndrome with other pathological lesion in kidney | Nephrotic syndrome with other specified pathological lesion in kidney | Nephrotic syndrome with unspecified pathological lesion in kidney | Syndrome nephrotic | Nephrotic syndrome worsened | Steroid-resistant nephrotic syndrome | Nephroses |
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| ADR Related Proteins |
| Protein Name |
UniProt AC |
TTD Target ID |
| Not Available | Not Available | Not Available |
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| Drugs Leading to the ADR |
| Drug ID | Drug Name | ADR Frequency (FAERS) | ADR Severity Grade (FAERS) | | BADD_D02504 | Lorlatinib | 0.000533% | |
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